As of 2023, private non-profit expenditure on R&D in all sectors in the US stood at 32.23 billion USD. The forecast from 2024 to 2028 indicates a steady increase, starting from 33.14 billion USD in 2024 to 36.64 billion USD in 2028. This represents a consistent year-on-year growth of approximately 2.9% over the forecasted period, reflecting the sector's ongoing investment commitment. Over these five years, the compound annual growth rate (CAGR) is about 2.57%.

Future trends to watch for include:

Potential increase in government policies supporting non-profit R&D funding.
Impact of emerging technologies demanding greater non-profit collaboration and investment.
Potential economic fluctuations affecting philanthropic R&D contributions.